Can smallpox come back?
Matthew Alvarez
Published Apr 24, 2026
Because smallpox no longer occurs naturally, scientists are only concerned that it could reemerge through bioterrorism.
Does smallpox still exist today?
The last naturally occurring case of smallpox was reported in 1977. In 1980, the World Health Organization declared that smallpox had been eradicated. Currently, there is no evidence of naturally occurring smallpox transmission anywhere in the world.What if smallpox returned?
Smallpox returning could result in blindness, terrible disfigurement and death for millions or even billions.What Old diseases are coming back?
Worrisome Diseases That Are Still Around
- Plague. 1/13. It's hard to believe, but the Black Death isn't just one for the history books or far-flung places. ...
- Tuberculosis (TB) 2/13. ...
- Syphilis and Chlamydia. 3/13. ...
- Scarlet Fever. 4/13. ...
- Measles. 5/13. ...
- Mumps. 6/13. ...
- Whooping Cough. 7/13. ...
- Legionnaires' Disease. 8/13.
How did smallpox start again?
Like Covid-19, smallpox is thought to have jumped from animals to humans. It is spread through coughs and sneezes, and lives on surfaces, particularly the bedding and clothing of those with the disease, as sores leak the virus, even when crusted over. Smallpox is mild for some, deadly for others.Could Smallpox Ever Come Back?
When was the last case of smallpox?
Thanks to the success of vaccination, the last natural outbreak of smallpox in the United States occurred in 1949. In 1980, the World Health Assembly declared smallpox eradicated (eliminated), and no cases of naturally occurring smallpox have happened since.What animal did smallpox come from?
Smallpox is an acute, contagious disease caused by the variola virus, a member of the genus Orthopoxvirus, in the Poxviridae family (see the image below). Virologists have speculated that it evolved from an African rodent poxvirus 10 millennia ago.Is the Black Death coming back?
New cases of the bubonic plague found in China are making headlines. But health experts say there's no chance a plague epidemic will strike again, as the plague is easily prevented and cured with antibiotics.What are the 7 diseases?
In the following pages, we present seven infections from the past that still plague us today.
- Pneumonic/Bubonic Plague. ...
- Spanish and Swine Flu -- H1N1. ...
- Polio. ...
- Chagas Disease. ...
- Leprosy. ...
- Hookworm. ...
- Tuberculosis.
What diseases no longer exist?
Eradicated diseases
- So far, only two diseases have been successfully eradicated—one specifically affecting humans (smallpox), and one affecting a wide range of ruminants (rinderpest).
- Smallpox is the first disease, and so far the only infectious disease of humans, to be eradicated by deliberate intervention.